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KMID : 0903520090520050568
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2009 Volume.52 No. 5 p.568 ~ p.572
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Aldose Reductase Inhibitory Activity of the Compounds from the Seed of Psoralea corylifolia
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Shim Sang-Hee
Kim Yu-Jin
Lee Joo-Young
Song Dae-Geun
Pan Cheol-Ho
Jung Sang-Hoon
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Abstract
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The purpose of this study was to evaluate the active properties of Psoralea corylifolia seed for the treatment of diabetic complications. 6-Prenylnaringenin (5) and corylin (6) isolated from P.corylifolia could possibly be acting as the active compounds for the inhibition of aldose reductase and would be the lead compounds for the aldose reductase inhibitors.
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KEYWORD
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aldose reductase, corylin, 6-prenylnaringenin, Psoralea corylifolia
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